The CEO of UnitedHealthcare was shot and killed in midtown Manhattan Wednesday morning in an apparent targeted attack as he was about to attend the company’s annual investor conference, a law enforcement official tells CNN. The gunman remains on the loose.

Brian Thompson was walking toward the New York Hilton Hotel in Midtown Manhattan, dressed in a suit and tie, to attend UnitedHealthcare’s annual investor conference being held in the ballroom.

A gunman, masked in the freezing temperatures, waited for about 10 minutes before Thompson’s arrival before opening fire[B] [/B]multiple times, striking Thompson from about 20 feet away, investigators tell CNN.

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